Single Cell Rna Qc

🏢Official
by anthropics · vlatest · Repository

This skill automates RNA quality control for single-cell data, ensuring reliable analysis and accurate research results.

Install on your platform

We auto-selected Claude Code based on this skill’s supported platforms.

1

Run in terminal (recommended)

terminal
claude mcp add anthropics-single-cell-rna-qc npx -- -y @trustedskills/anthropics-single-cell-rna-qc
2

Or manually add to ~/.claude/settings.json

~/.claude/settings.json
{
  "mcpServers": {
    "anthropics-single-cell-rna-qc": {
      "command": "npx",
      "args": [
        "-y",
        "@trustedskills/anthropics-single-cell-rna-qc"
      ]
    }
  }
}

Requires Claude Code (claude CLI). Run claude --version to verify your install.

About This Skill

What it does

This skill performs quality control (QC) on single-cell RNA sequencing (scRNA-seq) data. It identifies and filters out low-quality cells and genes, ensuring robust downstream analysis. The tool helps researchers improve the accuracy and reliability of their scRNA-seq experiments by removing noise and artifacts.

When to use it

  • Before performing differential gene expression analysis on scRNA-seq datasets.
  • When dealing with scRNA-seq data exhibiting high dropout rates or technical variation.
  • To prepare scRNA-seq data for clustering, trajectory inference, or other downstream analyses.
  • For initial exploration and cleaning of newly generated scRNA-seq data.

Key capabilities

  • Cell filtering based on quality metrics (e.g., number of detected genes).
  • Gene filtering based on expression thresholds.
  • Data normalization.
  • Identification of outlier cells.

Example prompts

  • "Perform QC on my scRNA-seq data and filter out cells with fewer than 500 expressed genes."
  • “Normalize the gene counts in this single-cell dataset.”
  • "Identify and remove outlier cells from this scRNA-seq experiment."

Tips & gotchas

The skill requires properly formatted scRNA-seq count matrices as input. Ensure your data is appropriately structured before using the tool to avoid errors.

Tags

🛡️

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Details

Version
vlatest
License
Author
anthropics
Installs
14

🏢 Official

Published by the company or team that built the technology.