Bio Restriction Enzyme Selection
CheckedThis tool intelligently selects appropriate restriction enzymes for DNA cloning based on your target sequence, streamlining experimental design and improving success rates.
Install on your platform
Showing Claude Code. One command installs this skill into any of the agents below.
- 1
Run this in your project
terminal$ npx skills add gptomics/bioskills --skill bio-restriction-enzyme-selection --full-depth -a claude-code Uses the open-source
skillsCLI and needs Node.js. Add-gto install it for your user instead of this project.
What we know about this skill
Publisher
gptomics
Taken from the source listing. We haven't verified who controls this account.
Install target
Live repository
Not pinned. Installing fetches whatever the repository holds at the time you run the command.
Automated safety checks
This skill passed all 6 checks. We read its files at one commit and looked for the things that make a skill dangerous to run — not for whether it works.
Declares what it does: passed
SKILL.md parses and declares a name and a description.
SKILL.md exists, its frontmatter parses, and it declares a name and a description.
No undeclared network calls: passed
Makes no network calls.
Every host the skill dials — from its scripts, its config endpoints or the commands it tells the agent to run — is either well-known package and API infrastructure or declared in its own frontmatter. Links in documentation are not counted.
No obfuscated payloads: passed
No encoded or obfuscated payloads.
No base64, hex or compressed blob is decoded and then executed, and no encoded shell commands.
No credential access: passed
Reads no keys, tokens, keychains or credential files.
Neither the code nor the SKILL.md instructions read SSH keys, cloud credentials, keychains, token stores, browser cookie databases or dotfiles that hold secrets.
No pipe-to-shell installers: passed
No pipe-to-shell or download-and-run installers.
No `curl … | sh` pattern, in the code or in the instructions, that runs code fetched at run time.
Pinned to a commit: passed
Scanned gptomics/bioskills at d91ed3d563.
The exact upstream commit SHA that was scanned is recorded, so the result refers to specific bytes.
- Commit
- d91ed3d563
- Scanned
- 4 files, 421 lines
About this skill
What it does
This skill allows users to select appropriate restriction enzymes for DNA digestion based on provided sequence data. It identifies potential enzyme recognition sites within a given DNA sequence and suggests suitable enzymes that can be used for cutting at those locations. The tool aims to streamline the process of designing molecular biology experiments involving DNA manipulation.
When to use it
- Planning PCR cloning: Determine which restriction enzymes will cut both your insert and vector for seamless ligation.
- Designing CRISPR-Cas9 experiments: Identify potential off-target sites by searching for sequences similar to guide RNAs.
- Analyzing DNA fragments: Predict the cutting pattern of a specific enzyme on a known DNA sequence.
- Troubleshooting digestion reactions: Verify if a chosen restriction enzyme will effectively cut a target DNA fragment.
Key capabilities
- Restriction enzyme recognition site identification
- DNA sequence analysis
- Enzyme selection based on sequence data
- Potential cutting site prediction
Example prompts
- "Find restriction enzymes that cut this DNA sequence: ATGCGTAC..."
- "What restriction sites are present in the following sequence?"
- "Suggest enzymes for digesting a vector with this insert."
Tips & gotchas
The accuracy of enzyme selection depends on the quality and completeness of the provided DNA sequence. Ensure the input sequence is free from errors to obtain reliable results.