Opentargets Database
Helps with AI, database as part of working with databases and data persistence workflows.
Install on your platform
We auto-selected Claude Code based on this skill’s supported platforms.
Run in terminal (recommended)
claude mcp add k-dense-ai-opentargets-database npx -- -y @trustedskills/k-dense-ai-opentargets-database
Or manually add to ~/.claude/settings.json
{
"mcpServers": {
"k-dense-ai-opentargets-database": {
"command": "npx",
"args": [
"-y",
"@trustedskills/k-dense-ai-opentargets-database"
]
}
}
}Requires Claude Code (claude CLI). Run claude --version to verify your install.
About This Skill
What it does
This skill provides access to the Open Targets database, a comprehensive resource for drug target identification and prioritization. It allows AI agents to query this data to retrieve information on genes, diseases, pathways, and potential therapeutic targets. The database integrates genomic, pharmacological, and clinical data to offer insights into disease mechanisms and identify promising intervention points.
When to use it
- Drug Discovery Research: Identify potential drug targets for a specific disease based on genetic associations or pathway involvement.
- Literature Review: Quickly gather information about the role of a gene in multiple diseases, streamlining research efforts.
- Target Prioritization: Evaluate and rank potential therapeutic targets based on data from Open Targets' integrated database.
- Pathway Analysis: Explore biological pathways associated with a disease or target to understand complex interactions.
Key capabilities
- Gene-disease associations
- Pharmacological evidence for drug targets
- Clinical trial information related to targets and diseases
- Pathway involvement data
- Target prioritization scores
Example prompts
- "What genes are associated with Alzheimer's disease according to the Open Targets database?"
- "Show me pharmacological evidence for targeting gene EGFR in cancer."
- “Which pathways are significantly impacted by mutations in TP53?”
Tips & gotchas
The Open Targets database is vast. Be specific with your queries to narrow down results and avoid overwhelming the AI agent. Understanding basic biological terminology will improve prompt effectiveness.
Tags
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Security Audits
| Gen Agent Trust Hub | Pass |
| Socket | Pass |
| Snyk | Pass |
🌐 Community
Passed automated security scans.