Opentargets Database
Queries microck's Open Targets database to retrieve drug target information, pathways, and disease associations for specified genes or compounds.
Install on your platform
We auto-selected Claude Code based on this skill’s supported platforms.
Run in terminal (recommended)
claude mcp add microck-opentargets-database npx -- -y @trustedskills/microck-opentargets-database
Or manually add to ~/.claude/settings.json
{
"mcpServers": {
"microck-opentargets-database": {
"command": "npx",
"args": [
"-y",
"@trustedskills/microck-opentargets-database"
]
}
}
}Requires Claude Code (claude CLI). Run claude --version to verify your install.
About This Skill
What it does
This skill provides access to the Open Targets database, a comprehensive resource for drug target identification and prioritization. It allows you to query information about diseases, genes, pathways, and potential therapeutic targets, including evidence supporting their involvement in disease. The data is sourced from multiple scientific sources and curated by experts.
When to use it
- Researching potential drug targets for a specific disease (e.g., "What are the key genetic drivers of Alzheimer's disease?").
- Identifying genes associated with a particular pathway or biological process.
- Exploring evidence supporting a gene as a therapeutic target.
- Finding information about clinical trials targeting specific genes or pathways.
Key capabilities
- Disease querying: Retrieve genes and targets associated with diseases.
- Gene querying: Find disease associations for a given gene.
- Pathway analysis: Explore pathways related to diseases or genes.
- Target prioritization: Access evidence scores and rankings of potential therapeutic targets.
Example prompts
- "What are the Open Targets data findings on the role of TP53 in cancer?"
- "List genes associated with Parkinson's disease according to the Open Targets database."
- "Show me the target prioritisation score for STK11 in pancreatic cancer."
Tips & gotchas
The Open Targets database is vast and complex. Be specific with your queries to get relevant results, and understand that evidence scores represent a curated assessment of data from multiple sources.
Tags
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| Socket | Pass |
| Snyk | Pass |
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