Opentargets Database
ListedAccess and query Davila7's curated open-targets database for drug target information, pathways, and disease associations.
Install on your platform
Showing Claude Code. One command installs this skill into any of the agents below.
- 1
Run this in your project
terminal$ npx skills add davila7/claude-code-templates --skill opentargets-database -a claude-code Uses the open-source
skillsCLI and needs Node.js. Add-gto install it for your user instead of this project.
What we know about this skill
Publisher
davila7
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Install target
Live repository
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About this skill
The opentargets-database skill enables AI agents to query the Open Targets Platform, a comprehensive resource for drug target validation. It allows agents to retrieve evidence-based scores, genetic associations, and clinical trial data for specific gene-disease pairs or therapeutic targets. This capability supports rapid hypothesis generation in biomedical research by providing access to curated datasets from multiple sources.
When to use it
- Investigating the potential of a novel drug target against a specific disease mechanism.
- Gathering evidence-based scores to prioritize candidates for wet-lab validation experiments.
- Retrieving genetic association data (e.g., GWAS hits) linked to therapeutic targets.
- Analyzing clinical trial status and outcomes for existing drugs targeting a specific pathway.
Key capabilities
- Querying the Open Targets database via API endpoints.
- Fetching drug-target interaction scores and confidence metrics.
- Accessing genetic association data linking variants to diseases.
- Retrieving information on clinical trials associated with specific targets.
- Parsing structured JSON responses for downstream analysis.
Example prompts
- "Query the Open Targets database for all drugs targeting the TP53 gene and return their interaction scores."
- "Find genetic associations between the BRCA1 gene and breast cancer from the Open Targets platform."
- "Retrieve clinical trial data for inhibitors of the EGFR pathway using the opentargets-database skill."
Tips & gotchas
Ensure your AI agent has valid API credentials or network access to reach the Open Targets servers, as direct browser-based queries may be blocked by CORS policies. Results are dependent on the current state of the Open Targets database, so verify data currency if making time-sensitive decisions.