Tooluniverse Adverse Event Detection
CheckedDetects potential adverse events from clinical notes using ToolUniverse, improving patient safety monitoring and rapid response identification.
Install on your platform
Showing Claude Code. One command installs this skill into any of the agents below.
- 1
Run this in your project
terminal$ npx skills add mims-harvard/tooluniverse --skill tooluniverse-adverse-event-detection -a claude-code Uses the open-source
skillsCLI and needs Node.js. Add-gto install it for your user instead of this project.
What we know about this skill
Publisher
mims-harvard
Taken from the source listing. We haven't verified who controls this account.
Install target
Live repository
Not pinned. Installing fetches whatever the repository holds at the time you run the command.
Automated safety checks
This skill passed all 6 checks. We read its files at one commit and looked for the things that make a skill dangerous to run — not for whether it works.
Declares what it does: passed
SKILL.md parses and declares a name and a description.
SKILL.md exists, its frontmatter parses, and it declares a name and a description.
No undeclared network calls: passed
Makes no network calls.
Every host the skill dials — from its scripts, its config endpoints or the commands it tells the agent to run — is either well-known package and API infrastructure or declared in its own frontmatter. Links in documentation are not counted.
No obfuscated payloads: passed
No encoded or obfuscated payloads.
No base64, hex or compressed blob is decoded and then executed, and no encoded shell commands.
No credential access: passed
Reads no keys, tokens, keychains or credential files.
Neither the code nor the SKILL.md instructions read SSH keys, cloud credentials, keychains, token stores, browser cookie databases or dotfiles that hold secrets.
No pipe-to-shell installers: passed
No pipe-to-shell or download-and-run installers.
No `curl … | sh` pattern, in the code or in the instructions, that runs code fetched at run time.
Pinned to a commit: passed
Scanned mims-harvard/tooluniverse at f5c37eebeb.
The exact upstream commit SHA that was scanned is recorded, so the result refers to specific bytes.
- Commit
- f5c37eebeb
- Scanned
- 16 files, 3,669 lines
- Copies in repo
- 3 — all of them scanned
About this skill
What it does
This skill, Tooluniverse Adverse Event Detection, automatically identifies and analyzes potential adverse drug events from clinical data. It leverages a pipeline incorporating FAERS disproportionality analysis, FDA label mining, mechanism-based prediction, and literature evidence to generate a quantitative Safety Signal Score (0-100). The goal is to improve patient safety monitoring and enable rapid response identification by quantifying signals for regulatory and clinical decision-making.
When to use it
- When investigating reports of unexpected adverse events associated with a drug.
- To prioritize serious adverse events like deaths or hospitalizations for immediate analysis.
- For assessing the potential risk of a new drug based on available data sources.
- To determine if an observed adverse event is specific to a drug, common across a class, or potentially due to confounding factors.
Key capabilities
- Adverse Event Signal Detection: Identifies adverse events reported more than expected using statistical thresholds (PRR >= 2.0, N >= 3, lower CI > 1.0).
- Quantitative Scoring: Generates a Safety Signal Score (0-100) to quantify the severity and likelihood of an adverse event.
- Multi-Source Data Integration: Combines data from FAERS, FDA labels, OpenTargets, DrugBank, and literature sources.
- Mechanism of Action Analysis: Uses tools like
OpenTargets_get_drug_mechanisms_of_action_by_chemblIdanddrugbank_get_targets_by_drug_name_or_drugbank_idto assess biological plausibility. - Evidence Grading: Assigns evidence grades (T1-T4) to support findings.
Example prompts
- "Analyze the adverse event 'myocardial infarction' associated with drug X."
- "What is the Safety Signal Score for 'liver failure' and drug Y?"
- "Is the adverse event 'rash' biologically plausible given the mechanism of action of drug Z?"
Tips & gotchas
- Always use English drug names when interacting with ToolUniverse tools.
- The skill prioritizes serious adverse events (deaths, hospitalizations) for analysis.
- Results are based on statistical thresholds and data from specific sources; consider these limitations when interpreting findings.